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American cutaneous leishmaniasis in infancy and childhood
Alberto E Paniz-Mondolfi1,2, Carolina Talhari3, María F García Bustos4
1Department of Infectious Diseases and Tropical Medicine/Infectious Diseases Pathology Laboratory, Hospital Internacional, Barquisimeto, Venezuela.
Insights
Cutaneous leishmaniasis is a common tropical skin disease affecting infants and children. This review details its clinical, diagnostic, and therapeutic aspects for pediatricians managing this parasitic infection.
Area of Science:
- Tropical medicine
- Pediatric dermatology
- Infectious diseases
Background:
- Infant and young child skin diseases are prevalent in tropical regions.
- The skin's direct environmental exposure makes it susceptible to climatic factors, vectors, and microorganisms, exemplified by leishmaniasis.
- Cutaneous leishmaniasis in children in the Americas is a significant concern, with potential for peri- and intradomiciliary transmission.
Purpose of the Study:
- To provide a comprehensive overview of cutaneous leishmaniasis in children.
- To consolidate key information on clinical, physiopathological, epidemiological, diagnostic, and therapeutic aspects.
- To serve as a practical reference for pediatricians dealing with tropical cutaneous pathology.
Main Methods:
- Literature review focusing on cutaneous leishmaniasis in infants and young children.
- Synthesis of information covering clinical presentation, disease mechanisms, transmission, diagnosis, and treatment.
- Emphasis on epidemiological data relevant to the Americas.
Main Results:
- Cutaneous leishmaniasis presents a notable morbidity in young populations in tropical areas.
- Increased exposure risk in children is linked to domestic transmission patterns.
- A multi-faceted approach is required for effective management, encompassing various stages of the disease.
Conclusions:
- Cutaneous leishmaniasis is a significant pediatric dermatological challenge in the tropics.
- Understanding transmission dynamics, particularly peri- and intradomiciliary routes, is crucial for prevention and control.
- This review offers essential knowledge for pediatricians to effectively diagnose and manage this parasitic skin disease.
Abstract:
Infant and young child skin diseases are among the most common features of morbidity throughout the tropics. Because the skin is directly exposed to the environment, it is considerably affected by climatic and local conditions such as vectors and microorganisms, as in the case of leishmaniasis. In America the observed magnitude of cutaneous leishmaniasis in children has led to the study of increased risk of exposure of this group due to the possibility of peri- and intradomiciliary transmission. The present review pretends to make a concrete approach all through the broad and main figures of this parasitic disease, including the clinical, physiopathological, epidemiological, diagnostic, and therapeutic aspects, in order to be used as a practical source of reference for pediatricians leading with tropical cutaneous pathology in the region.
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