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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Anaphylaxis and intimate behaviour.

Gennaro Liccardi1, Marco Caminati, Gianenrico Senna

  • 1aDepartment of Pulmonology, Haematology and Oncology, Division of Pneumology and Allergology, High Speciality 'A.Cardarelli' Hospital, Naples bPostgraduate School of Respiratory Medicine, Department of Systems Medicine, University of Rome 'Tor Vergata', Rome cAllergy Unit and Asthma Center, Verona University and General Hospital, Verona dDepartment of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.

Current Opinion in Allergy and Clinical Immunology
|July 26, 2017
PubMed
Summary
This summary is machine-generated.

Intimate contact can expose individuals to allergens, triggering allergic reactions. Understanding sex-related allergies is crucial for diagnosis and improving quality of life.

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Area of Science:

  • Allergy and Immunology
  • Sexual Health

Background:

  • Intimate behaviors can be routes of allergen exposure.
  • Sex-related allergies arise from triggers common in sexual situations.

Purpose of the Study:

  • To review current knowledge on sexual-related allergies.
  • To increase awareness and understanding of these allergies among clinicians.

Main Methods:

  • Literature review on intimate behaviors and allergic reactions.
  • Analysis of case studies and proposed mechanisms.

Main Results:

  • Kissing can cause IgE-mediated reactions via allergen transfer (e.g., peanuts, beta-lactams).
  • Kissing may also induce allergic sensitization.
  • Seminal plasma hypersensitivity (related to prostate-specific antigen) causes symptoms during intercourse.
  • Successful desensitization protocols have been reported for seminal plasma hypersensitivity.

Conclusions:

  • Intimate contact is a potential route for allergen exposure.
  • The prevalence of sex-related allergies is unknown but impacts quality of life.
  • Clinicians should consider sex and allergy links for diagnosing unexplained conditions.