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Androgenic-anabolic steroids inhibited post-exercise hypotension: a case control study
Jefferson F C R Junior1, Alexandre S Silva2, Glêbia A Cardoso2
1Universidade Federal do Piauí(UFPI), Campus Universitário Ministro Petrônio Portella, Department of Biophysics and Physiology, Teresina, PI, Brazil.
Brazilian Journal of Physical Therapy
|July 27, 2017
Summary
Anabolic androgenic steroid (AAS) users exhibit impaired post-exercise blood pressure reduction. This study shows reduced systolic post-exercise hypotension in AAS users, indicating a new adverse effect of AAS.
Area of Science:
- Exercise Physiology
- Cardiovascular Health
- Sports Medicine
Background:
- Anabolic androgenic steroids (AAS) are linked to hypertension.
- Exercise acutely lowers blood pressure, but AAS effects on this are unknown.
Purpose of the Study:
- To investigate the post-exercise blood pressure response in AAS users compared to controls.
Main Methods:
- Thirteen AAS users and sixteen controls performed aerobic exercise.
- Blood pressure and heart rate were monitored pre- and post-exercise for 60 minutes.
- Repeated measures ANOVA analyzed group differences.
Main Results:
- Controls showed significant systolic blood pressure reduction post-exercise (up to 13.9±11.6mmHg).
- AAS users had significantly blunted systolic post-exercise hypotension (max reduction 6.2±11.5mmHg).
- No significant diastolic post-exercise hypotension was observed in either group.
Conclusions:
- AAS usage is associated with impaired systolic post-exercise hypotension.
- This represents a novel adverse cardiovascular effect of AAS.
- Further research is needed to understand the clinical implications.
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