[Animal experiment studies on improving ischemia tolerance of the testis]

The reactions of the germinative testicular epithelium after definite ischemia periods were studied in rats. Using heparin the testicular ischemia tolerance has already been prolonged; this can be distinctly improved by adding alphareceptor blockers. The consequences of a 30 min and 2 h period of testicular ischemia are nearly eliminated by the described medicamentous combination. The experimental results show that at present the use of heparin and alpha-receptor blockers seems to be the best way, to extend the ischemia tolerance during autotransplantation of testicles.