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Updated: Jul 28, 2026

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
Published on: December 23, 2016
Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies
JoAnn L Yee1, Richard Grant2, Koen K Van Rompay1
1California National Primate Research Center, University of California, Davis, CA, USA.
Abstract:
To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.
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