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Updated: Feb 25, 2026

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques
Published on: May 2, 2017
Long-term efficient control of SIV infection in macaques is associated with an intact intestinal barrier
Maria Daskalaki1, Berit Neumann1, Antonina Klippert1
1Unit of Infection Models, Leibniz Institute for Primate Research, German Primate Center, Goettingen, Germany.
Abstract:
Hallmarks of SIV infection are early depletion of gut CD4 T cells and diminished intestinal integrity. Comprehensive studies on colon biopsies of SIV-infected macaques efficiently controlling infection revealed that in contrast to viremic and failing controllers, elite controllers show preserved CD4 T cells, and low viral load, apoptosis, and inflammation.
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