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Changing concepts in hypertension management

P S Gudsoorkar1,2, S W Tobe3

  • 1Department of Medicine, Clinical Fellow Adult Renal Transplant, Multi Organ Transplant Program, University Health Network, Toronto, ON, Canada.

Journal of Human Hypertension
|July 28, 2017
PubMed

Insights

New hypertension guidelines, informed by SPRINT and HOPE-3 trials, emphasize automated blood pressure measurement and impact treatment targets, especially for resistant hypertension.

Area of Science:

  • Cardiology
  • Clinical Practice Guidelines
  • Hypertension Management

Background:

  • Hypertension is a primary modifiable risk factor for cardiovascular disease (CVD) and mortality.
  • Antihypertensive medications reduce target organ damage and prevent CVD events.
  • Recent trials like SPRINT and HOPE-3 are poised to influence clinical practice.

Purpose of the Study:

  • To review recent hypertension trials, including SPRINT and HOPE-3.
  • To contextualize these findings within existing clinical practice guidelines.
  • To describe the anticipated impact on hypertension management strategies.

Main Methods:

  • Review of landmark hypertension trials (SPRINT, HOPE-3) and prior guidelines.
  • Analysis of the implications for treatment thresholds and targets.
  • Evaluation of effects on elderly populations and resistant hypertension management.

Main Results:

  • SPRINT and HOPE-3 trials will likely alter hypertension management protocols.
  • A shift towards automated blood pressure measurement is evident.
  • Guidelines will be updated regarding treatment thresholds, targets, and special populations.

Conclusions:

  • Recent hypertension research necessitates updates to clinical practice guidelines.
  • Management strategies, including for resistant hypertension and the elderly, will evolve.
  • Automated blood pressure monitoring is becoming standard in hypertension care.

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