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From engineering to editing the rat genome.

Stephen Meek1, Tomoji Mashimo2,3, Tom Burdon4

  • 1The Roslin Institute and R(D)VS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK. stephen.meek@roslin.ed.ac.uk.

Mammalian Genome : Official Journal of the International Mammalian Genome Society
|July 29, 2017
PubMed
Summary

Laboratory rats are vital biomedical research models. Advances in embryonic stem cell technology and CRISPR/Cas gene editing now enable precise genetic engineering for creating new rat models to study human diseases.

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