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Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
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Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage
Anil Can1, Victor M Castro2, Yildirim H Ozdemir1
1Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, 02115, USA.
Translational Stroke Research
|July 29, 2017
Summary
Current alcohol consumption significantly increases the risk of intracranial aneurysm rupture. However, this risk diminishes after cessation, highlighting the importance of quitting alcohol to prevent aneurysm rupture.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Intracranial aneurysms are a significant cause of cerebrovascular disease.
- Alcohol consumption is a potentially modifiable risk factor for aneurysm rupture.
Purpose of the Study:
- To investigate the association between alcohol consumption, its intensity, and the rupture of intracranial aneurysms.
- To evaluate the impact of alcohol cessation on aneurysm rupture risk.
Main Methods:
- Retrospective review of 6411 intracranial aneurysms in 4701 patients (1990-2016).
- Comparison of cases with ruptured aneurysms versus controls with unruptured aneurysms.
- Univariable and multivariable logistic regression analyses to assess alcohol consumption's role.
Main Results:
- Current alcohol use was significantly associated with a higher risk of aneurysm rupture (OR 1.36).
- Increased daily alcohol intake among current users correlated with rupture risk (OR 1.13 per beverage).
- Former alcohol use did not show a significant association with rupture status.
Conclusions:
- Current alcohol consumption and its intensity are linked to increased intracranial aneurysm rupture risk.
- Alcohol cessation may mitigate the elevated risk of aneurysm rupture.
- Identifying and modifying alcohol consumption behaviors is crucial for preventing aneurysm rupture.
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