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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...

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Updated: May 13, 2026

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening
15:28

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening

Published on: January 17, 2014

Leveraging Social Risk Factor Screening Infrastructure in Rheumatology Clinics to Respond to Rising Rates of

Rebecca Summit1, Dylan B Tierney2,3,4,5, Taussia Boadi1

  • 1Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

ACR Open Rheumatology
|May 12, 2026
PubMed
Summary
This summary is machine-generated.

Individuals with rheumatic conditions and housing instability face higher tuberculosis (TB) risks. A social risk screening alert prompted rheumatologists to identify and screen at-risk patients for TB, despite varied responses.

Related Experiment Videos

Last Updated: May 13, 2026

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening
15:28

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening

Published on: January 17, 2014

Area of Science:

  • Public Health
  • Rheumatology
  • Infectious Disease

Background:

  • Immunocompromised patients with rheumatic diseases are at increased risk for tuberculosis (TB).
  • Socially vulnerable populations, including those experiencing homelessness, face heightened TB risks.
  • An alert regarding increased TB rates among homeless individuals in Massachusetts necessitated proactive identification of high-risk patients.

Purpose of the Study:

  • To leverage existing social risk screening infrastructure within rheumatology practices to identify and manage TB risk in vulnerable patients.
  • To assess the feasibility and effectiveness of a rapid response system triggered by a public health alert.

Main Methods:

  • Identified patients with rheumatic conditions on immunosuppressive medications and experiencing housing instability using EHR data.
  • Notified rheumatologists about TB risks and provided screening information.
  • Monitored EHRs for TB screening documentation, orders, and laboratory results post-alert.

Main Results:

  • Thirty-three patients with rheumatic conditions and housing instability were identified.
  • Of these, 23 patients on immunosuppressants were targeted for TB screening.
  • Post-alert actions included symptom screening documentation (13%), T-SPOT orders (30% after reminder), symptom review (22%), and patient messaging (18%).

Conclusions:

  • The rheumatology social risk screening infrastructure enabled a swift response to a public health concern.
  • Rheumatologists' engagement varied, potentially due to clinical pressures.
  • Despite challenges in patient outreach, significant screening actions were initiated, with ongoing efforts to improve TB screening for vulnerable populations.