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Related Concept Videos

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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
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When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
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Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
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Related Experiment Video

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Author Spotlight: Enhancing Neurorehabilitation Through EEG, Motor Imagery, and Virtual Reality
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Desktop Genetics.

Soren H Hough1, Ayokunmi Ajetunmobi1, Leigh Brody1

  • 1Desktop Genetics Ltd, London, E1 6QR, UK.

Personalized Medicine
|August 1, 2017
PubMed
Summary

Desktop Genetics is developing a gene-editing platform using artificial intelligence for personalized medicine. Their novel system aims to revolutionize therapeutic development by learning from CRISPR experiments and genomic data.

Keywords:
CRISPRbioinformaticsbiomedical researchdesigngeneticsgenomicssgRNA

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Area of Science:

  • Bioinformatics
  • Genomics
  • Personalized Medicine

Background:

  • Desktop Genetics is creating a gene-editing platform focused on personalized medicine.
  • The platform utilizes clustered regularly interspaced short palindromic repeats (CRISPR) technology for experimental design and execution.
  • Collaboration with scientists globally is central to their approach.

Discussion:

  • The system integrates experimental data, single-guide RNA design principles, and international genomics project information.
  • Machine learning techniques are applied to this integrated data.
  • The goal is to create a cognitive therapeutic development tool.

Key Insights:

  • A novel CRISPR artificial intelligence system is under development.
  • The system learns from past CRISPR experiments and genomic data.
  • This approach aims to enhance the efficiency and effectiveness of therapeutic development.

Outlook:

  • The platform has the potential to revolutionize medicine through AI-driven therapeutic development.
  • Future applications may include accelerated drug discovery and tailored treatment strategies.
  • Continued advancements in machine learning will drive the platform's capabilities.