[Pediatric brain tumors]

W Reith1, S Bodea, R Mühl-Benninghaus2

  • 1Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße, 66421, Homburg/Saar, Deutschland. Wolfgang.Reith@uks.eu.

Der Radiologe
|August 3, 2017
PubMed

Insights

Pediatric brain tumors, such as medulloblastomas and low-grade astrocytomas, differ from adult brain tumors in histology and location. This review outlines key imaging criteria for common childhood brain tumors.

Area of Science:

  • Pediatric Oncology
  • Neuroradiology
  • Neuro-oncology

Background:

  • Brain tumors exhibit distinct histological and localization patterns in pediatric versus adult populations.
  • Malignant gliomas and meningiomas are common in adults, whereas medulloblastomas and low-grade astrocytomas are prevalent in children.
  • Pediatric brain tumors predominantly occur in the infratentorial region (50-70%), contrasting with the approximately 30% infratentorial incidence in adults.

Purpose of the Study:

  • To differentiate common pediatric brain tumors from adult types.
  • To highlight the characteristic locations and imaging features of pediatric brain tumors.
  • To provide essential imaging criteria for diagnosing common pediatric brain tumors.

Main Methods:

  • Review of diagnostic imaging modalities including sonography, cranial computed tomography (CCT), and magnetic resonance imaging (MRI).
  • Analysis of space-occupying characteristics, density, and intensity variations compared to normal brain parenchyma.
  • Description of extrusive growth, parenchymal infiltration, and intrinsic origins of tumors.

Main Results:

  • Identification of key differences in tumor types (e.g., medulloblastoma, astrocytoma) and their locations between pediatric and adult populations.
  • Recognition of brain tumors via imaging based on mass effect and signal/density alterations.
  • Outline of the most common pediatric brain tumors: astrocytoma, medulloblastoma, brainstem glioma, craniopharyngioma, neurofibromatosis, and ganglioglioma.

Conclusions:

  • Understanding the unique characteristics of pediatric brain tumors is crucial for accurate diagnosis.
  • Imaging plays a vital role in identifying and characterizing brain tumors in children.
  • This article provides a foundational overview of common pediatric brain tumors and their imaging criteria.

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