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Aliphatic Glucoside, Zanthoionic Acid and Megastigmane Glucosides: Zanthoionosides A-E from the Leaves of Zanthoxylum

Serika Teshima1, Susumu Kawakami2, Sachiko Sugimoto1

  • 1Graduate School of Biomedical and Health Sciences, Hiroshima University.

Chemical & Pharmaceutical Bulletin
|August 4, 2017
PubMed

Keywords:
RutaceaeZanthoxylum ailanthoidesmegastigmanezanthoionoside

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α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...
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