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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

2.8K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
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Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

675
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
675
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

658
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
658
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Neonatal Perforated Appendicitis Attributed to Localized Necrotizing Enterocolitis of the Appendix: A Review.

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Related Experiment Video

Updated: Feb 25, 2026

Author Spotlight: Enhancing Understanding and Treatment Strategies with the NEC-on-a-Chip Model
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Author Spotlight: Enhancing Understanding and Treatment Strategies with the NEC-on-a-Chip Model

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Neonatal Perforated Appendicitis Masquerading as Necrotizing Enterocolitis.

Andrew Tumen1, Pranit N Chotai1,2, John Matthew Williams1

  • 1Division of Pediatric Surgery, Le Bonehur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN, USA.

Journal of Neonatal Surgery
|August 4, 2017
PubMed
Summary
This summary is machine-generated.

Neonatal perforated appendicitis (NPA) can mimic necrotizing enterocolitis (NEC) in preterm infants. Early surgical intervention is crucial for suspected cases, highlighting the importance of clinical suspicion for accurate diagnosis and treatment.

Area of Science:

  • Neonatal surgery
  • Pediatric gastroenterology
  • Surgical pathology

Background:

  • Necrotizing enterocolitis (NEC) is a common gastrointestinal emergency in preterm neonates.
Keywords:
Localized NECNecrotizing enterocolitisNeonatal appendicitisNeonatal perforated appendicitis

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  • Appendicitis is rare in neonates, and perforation is even rarer.
  • Distinguishing NEC from other causes of abdominal distress is critical for timely management.