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Protein-Based Drug-Delivery Materials.
Dave Jao1,2, Ye Xue3,4, Jethro Medina5
1Department of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA. jaod07@students.rowan.edu.
Materials (Basel, Switzerland)
|August 5, 2017
Summary
Protein-based polymers offer biocompatible, sustainable solutions for controlled drug delivery, overcoming biological barriers for targeted therapies. This review explores their properties and applications in various medical treatments.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Drug Delivery Systems
Background:
- Chronic diseases require long-term, controlled drug release, posing challenges for therapeutic compound transport across biological barriers.
- Nanoscale protein-based polymers are emerging as promising carriers for drug and vaccine delivery due to their biocompatibility and biodegradability.
Purpose of the Study:
- To review protein-based polymers for sustained and controlled drug release.
- To compare protein-based polymers with synthetic alternatives.
- To highlight their properties, functionality, and applications in targeted drug delivery.
Main Methods:
- Review of literature on protein-based polymer sources, properties, and functionalities.
- Comparison of protein-based polymers with synthetic polymers.
- Elucidation of drug delivery efficiency based on material characteristics (e.g., molecular weight, particle size, shape, morphology, porosity).
Main Results:
- Protein-based polymers offer advantages over synthetic polymers, including biocompatibility, biodegradability, sustainability, and cost-effectiveness.
- Material characteristics significantly influence drug absorption and delivery efficiency.
- Protein composites can be functionalized for targeted drug delivery.
Conclusions:
- Protein-based polymers are versatile materials for advanced drug delivery systems.
- Their tunable properties enable enhanced therapeutic outcomes across diverse biomedical applications.
- Further research into protein-based materials promises innovative treatments for various diseases.
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