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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
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Imaging of Myopathies.

Lukas Filli1, Sebastian Winklhofer2, Gustav Andreisek3

  • 1Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.

Radiologic Clinics of North America
|August 5, 2017
PubMed
Summary

Magnetic Resonance (MR) imaging aids in diagnosing various myopathies, including inflammatory, muscular dystrophy, and congenital forms. Advanced MR techniques offer further insights into muscle disease characterization.

Keywords:
MR imagingMuscle dystrophyMyopathyMyositisSkeletal muscle

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Area of Science:

  • Musculoskeletal Radiology
  • Neuromuscular Disorders

Background:

  • Myopathies encompass a diverse group of muscle diseases affecting muscle function.
  • Accurate diagnosis is crucial for appropriate management and prognosis of myopathies.

Purpose of the Study:

  • To elucidate the current utility of Magnetic Resonance (MR) imaging in evaluating myopathies.
  • To outline characteristic MR imaging findings across different myopathy classifications.
  • To explore the emerging role of advanced MR techniques in muscle disease assessment.

Main Methods:

  • Review of current literature on MR imaging in myopathy diagnosis.
  • Discussion of typical MR imaging features for idiopathic inflammatory myopathies, muscular dystrophies, and congenital myopathies.
  • Overview of advanced MR imaging techniques, such as diffusion-weighted imaging and MR spectroscopy.

Main Results:

  • MR imaging demonstrates characteristic patterns that aid in differentiating various myopathies.
  • Specific findings help in classifying myopathies, including idiopathic inflammatory myopathies, muscular dystrophies, and congenital myopathies.
  • Advanced MR techniques show promise for more detailed tissue characterization and disease monitoring.

Conclusions:

  • MR imaging is an essential tool in the comprehensive assessment of myopathies.
  • Understanding typical and advanced MR imaging findings improves diagnostic accuracy and patient management.
  • Further research into advanced MR techniques will enhance their clinical application in neuromuscular diseases.