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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
STUDY OF WEAK D PHENOTYPE IN HETEROGENEOUS POPULATION
1Associate Professor, Dept of Transfusion Medicine, Armed Forces Medical College, Pune 411 040.
Abstract:
Weak D is the current phenotypic term used to denote a weakened expression of Rhesus (Rh) D antigen on red cells due to a quantitative or qualitative difference in Rh antigen. The present study was undertaken from January 1986 to August 1997. Out of a total of 5042 Rh D confirmation tests 22 (0.43%) weak D phenotypes were detected. Fifteen (68.3%) weak D phenotypes were from blood group O. Five (22.7%) from blood group A and one (4.5%) each from blood group B and AB. There were 15 males and 7 females. There were no cases of haemolytic disease of the newborn or Rh incompatibility.
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