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Hypersomnia in Neurodegenerative Diseases
Sushanth Bhat1, Sudhansu Chokroverty1
1Division of Sleep Medicine, Department of Neuroscience, JFK Neuroscience Institute, Seton Hall University, 65 James Street, Edison, NJ 08818, USA.
Sleep Medicine Clinics
|August 6, 2017
Summary
Hypersomnia, or excessive daytime sleepiness, is frequent in neurodegenerative diseases, impacting patient quality of life. This review covers its prevalence, causes, and management strategies in conditions like tauopathies and synucleinopathies.
Area of Science:
- Neurology
- Sleep Medicine
- Neurodegenerative Diseases
Background:
- Hypersomnia is a prevalent symptom in neurodegenerative conditions.
- It significantly diminishes patients' quality of life.
- Understanding its association with specific diseases is crucial.
Purpose of the Study:
- To explore the prevalence and contributing factors of hypersomnia in neurodegenerative diseases.
- To outline common nocturnal sleep disturbances leading to daytime hypersomnia.
- To discuss clinical approaches, diagnostics, and treatments for hypersomnia in this patient group.
Main Methods:
- Literature review of hypersomnia in neurodegenerative diseases.
- Analysis of factors associated with hypersomnia.
- Discussion of clinical management strategies.
Main Results:
- Hypersomnia is common across various neurodegenerative diseases, including tauopathies and synucleinopathies.
- Nocturnal sleep issues frequently underlie daytime hypersomnolence.
- A structured clinical approach and diagnostic testing are essential.
Conclusions:
- Effective management of hypersomnia in neurodegenerative diseases requires a comprehensive approach.
- Addressing nocturnal sleep problems is key to alleviating daytime hypersomnia.
- Further research into targeted treatments is warranted.
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