Toewebs as a source of gram-negative bacilli.

Area of Science:

• Microbiology
• Dermatology
• Occupational Health

Background:

• Gram-negative bacilli are frequently found on human skin.
• The toewebs can harbor various 'enteric' and 'environmental' bacteria.
• Understanding bacterial prevalence on feet is crucial for public health.

Purpose of the Study:

• To investigate the prevalence of Gram-negative bacilli on the toewebs in different population groups.
• To explore the relationship between Gram-negative bacilli and specific foot conditions and occupational exposures.
• To assess the feet as a potential source for infections.

Main Methods:

• Prevalence surveys of Gram-negative bacilli on toewebs.
• Comparison across groups: normal students, hospital outpatients (suspected Tinea pedis), industrial workers, and coal miners.
• Correlation analysis of bacterial presence with symptoms (itching, soreness, cracking/fissuring, malodour) and working conditions (wet environments, protective clothing).

Main Results:

• Prevalence varied significantly: 8% (students), 24% (outpatients), 41% (industrial workers), 58% (coal miners).
• Highest prevalence observed in individuals exposed to wet working conditions.
• Associations found between Gram-negative bacilli and specific symptoms, with variations across occupational groups.

Conclusions:

• The toewebs serve as a significant reservoir for Gram-negative bacilli, particularly in certain occupational settings.
• Wet working conditions increase the risk of Gram-negative bacilli colonization.
• Foot carriage of these bacteria may contribute to infections beyond the toewebs.