Photopolymerized water-soluble maleilated chitosan/methacrylated poly (vinyl alcohol) hydrogels as potential tissue
Yingshan Zhou1, Can Zhang2, Kaili Liang2
1College of Materials Science and Engineering, Wuhan Textile University, Wuhan 430073, People's Republic of China; Key Laboratory of Green Processing and Functional Textiles of New Textile Materials, Ministry of Education, Wuhan Textile University, Wuhan 430073, People's Republic of China.
Abstract:
Photocrosslinkable water-soluble maleilated chitosan and methacrylated poly (vinyl alcohol) were synthesized and therefore maleilated chitosan/methacrylated poly (vinyl alcohol) (MCS/MPVA) hydrogels were prepared under UV radiation. Series of properties of the hydrogels including rheological property, swelling behavior, morphology and mechanical test were investigated. The main results showed that the MCS/MPVA hydrogels had fast gel-forming rate (complete transformation to gel within 150s), improved compressive strength at 0.169±0.011MPa and rapid absorbent capacity. These behaviors could be tunable via the control of weight ratio of MCS to MPVA. The indirect cytotoxicity assessments demonstrated the photocrosslinked hydrogels was compatible to mouse fibroblasts (L929 cells), indicating their potential as tissue engineering scaffolds.
