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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
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[Metabolomic blood test: purpose, implementation and interpretation of data]
P G Lokhov1, A V Lisitsa1, A I Archakov1
1Institute of Biomedical Chemistry, Moscow, Russia.
Biomeditsinskaia Khimiia
|August 8, 2017
Summary
Metabolomic blood tests can detect numerous xenobiotics and disease markers, offering a comprehensive health overview. This approach aids in detoxification and monitoring, potentially increasing human lifespan by ensuring biochemical balance.
Area of Science:
- Biochemistry
- Toxicology
- Preventive Medicine
Background:
- The human body constantly encounters xenobiotics through diet, respiration, and medication.
- A significant burden of toxic substances and latent diseases negatively impacts health and longevity.
- Traditional diagnostic methods are insufficient for comprehensive screening of xenobiotics and diseases.
Purpose of the Study:
- To introduce and detail the purpose, implementation, and interpretation of metabolomic blood testing.
- To facilitate the adoption of metabolomic blood tests in the Russian Federation.
- To explore the potential of metabolomic testing to increase average life expectancy.
Main Methods:
- Non-targeted (review) metabolomic blood analysis to identify low molecular weight substances.
- Detection and quantification of xenobiotics and disease markers in blood.
- Monitoring of biochemical processes and "chemical purity" of the body.
Main Results:
- Metabolomic blood tests can reveal a vast array of xenobiotics and disease markers.
- The method allows for the detection of previously unidentifiable substances affecting health.
- It enables targeted detoxification and ongoing health monitoring.
Conclusions:
- Metabolomic blood testing is a crucial tool for assessing xenobiotic exposure and disease indicators.
- Monitoring "chemical purity" and biochemical normality via metabolomics is key to longevity.
- Implementing metabolomic analysis can significantly enhance average life expectancy.

