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Newer drug delivery systems in anesthesia
Sona Dave1, Deepa Shriyan1, Pinakin Gujjar1
1Department of Anaesthesiology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, Maharashtra, India.
Journal of Anaesthesiology, Clinical Pharmacology
|August 8, 2017
Summary
Newer drug delivery systems, including controlled release and closed-loop infusion, enhance existing medications for better patient outcomes and fewer side effects in anesthesiology. Clinicians must adapt to these advancements for improved safety and efficacy.
Area of Science:
- Pharmacology
- Anesthesiology
- Drug Delivery Systems
Background:
- The pharmaceutical industry is focusing on enhancing existing drug molecules rather than developing new ones due to cost.
- Current trends emphasize maximizing therapeutic benefits while minimizing adverse effects.
Purpose of the Study:
- To review novel drug delivery systems relevant to anesthesiology practice.
- To highlight the shift towards improved efficacy and safety in drug administration.
Main Methods:
- Review of current literature on advanced drug delivery technologies.
- Discussion of pharmacokinetic principles applied to drug dosing.
- Exploration of computer-assisted drug delivery systems.
Main Results:
- Controlled release, target-controlled infusion, and closed-loop infusion systems are gaining prominence.
- Pharmacokinetic-guided dosing improves drug safety and maintains steady plasma concentrations.
- Technologies previously confined to research are now integrated into clinical practice.
Conclusions:
- Anesthesiologists need to be familiar with emerging drug delivery technologies.
- These advancements offer potential for safer and more effective patient care.
- The review provides insights into modern drug delivery strategies for anesthesiology.
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