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Published on: July 8, 2025
Co-evolution techniques are reshaping the way we do structural bioinformatics
Saulo de Oliveira1, Charlotte Deane1
1Department of Statistics, University of Oxford, Oxford, UK.
Abstract:
Co-evolution techniques were originally conceived to assist in protein structure prediction by inferring pairs of residues that share spatial proximity. However, the functional relationships that can be extrapolated from co-evolution have also proven to be useful in a wide array of structural bioinformatics applications. These techniques are a powerful way to extract structural and functional information in a sequence-rich world.
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