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Heart Valves

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...

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Related Experiment Video

Updated: Feb 25, 2026

Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets

Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets

Published on: March 23, 2022

Weaving for heart valve tissue engineering.

Albert Liberski¹, Nadia Ayad², Dorota Wojciechowska³

¹Sustainability Division, College of Science & Engineering (CSE), Hamad Bin Khalifa University (HBKU), Doha, Qatar.

Biotechnology Advances

|August 8, 2017

Summary

This summary is machine-generated.

Woven scaffolds offer adaptable solutions for artificial heart valve tissue engineering (TE). This review bridges weaving and textile engineering for improved heart valve tissue engineering (HVTE) scaffolds.

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Area of Science:

Biomaterials Science
Tissue Engineering
Textile Engineering

Background:

Weaving technology provides adaptable solutions for artificial heart valve (HV) tissue engineering (TE).
The interlacing of yarns in weaving allows for the creation of complex, multi-layered scaffold architectures, mimicking natural tissue structures.
Cellular growth within woven scaffolds can be guided by yarn orientation, promoting oriented extracellular matrix deposition.

Purpose of the Study:

To bridge the fields of weaving technology and tissue engineering for heart valve applications.
To foster collaborative research between textile and tissue engineers in heart valve tissue engineering (HVTE).
To review woven medical products, patents, and publications relevant to heart valve tissue engineering.

Main Methods:

Literature review focusing on weaving technology applications in heart valve tissue engineering (HVTE).
Analysis of weaving techniques for creating multi-layered scaffolds.
Discussion of cell-scaffold interactions and guided tissue regeneration.

Main Results:

Woven scaffolds can replicate the three-layer architecture of heart valve leaflets.
Yarn orientation in woven scaffolds directs cell growth and extracellular matrix deposition.
Existing woven medical products and patents demonstrate the potential of this technology.

Conclusions:

Weaving is a promising technology for developing advanced artificial heart valve scaffolds.
Interdisciplinary collaboration between textile and tissue engineers is crucial for advancing HVTE.
Further exploration of weaving parameters is needed to optimize scaffold properties for heart valve regeneration.