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Chronic Kidney Disease-Mineral and Bone Disorder in Asia
Masafumi Fukagawa1, Hirotaka Komaba1,2
1Division of Nephrology, Endocrinology and Metabolism, Tokai University School of Medicine, Isehara, Japan.
Insights
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is common in CKD patients. Current guidelines lack Asian patient data, necessitating localized CKD-MBD management strategies.
Area of Science:
- Nephrology
- Endocrinology
- Bone Metabolism
Background:
- Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a frequent complication in chronic kidney disease (CKD) patients.
- CKD-MBD is a systemic condition requiring management focused on improving survival and reducing cardiovascular events and fractures.
Purpose of the Study:
- To highlight the need for CKD-MBD management strategies tailored to Asian populations.
- To emphasize the limitations of current guidelines based on non-Asian data.
Main Methods:
- Review of existing literature and guidelines on CKD-MBD.
- Analysis of the heterogeneity in medical systems and economic status across Asian regions.
Main Results:
- Global and local guidelines for CKD-MBD management often lack data from Asian CKD patients.
- Significant variations exist in healthcare systems and economic factors among Asian countries.
Conclusions:
- Establishing optimal, localized CKD-MBD management strategies requires dedicated analysis and sharing of Asian patient data.
- Further research and data dissemination are crucial for advancing CKD-MBD care in Asia.
Background:
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is one of the most common complications in patients with CKD. As CKD-MBD is a systemic syndrome, prevention and management should be aimed at achieving better survival and less risk of cardiovascular events and fractures.
Summary:
Although target ranges for serum markers of mineral metabolism have been proposed in several global or local guidelines, these were mostly based on data from non-Asian patients. Additionally, there remain differences in medical and social systems as well as in economic status, even among Asian countries and areas.
Key Message:
Asian CKD patient data needs to be analyzed, published, and shared to establish optimal local strategies for CKD-MBD management.
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