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The relationship between pulmonary hypertension and obstructive sleep apnea
Hang S Wong1, Adrian J Williams, YingJuan Mok
1aSleep Disorders Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK bChangi General Hospital, Simei, Singapore cKing's College London, London, UK.
Obstructive sleep apnea (OSA) can cause pulmonary hypertension, affecting 17-53% of patients. Continuous positive airway pressure is an effective treatment for this condition.
Area of Science:
- Cardiology
- Pulmonology
- Sleep Medicine
Background:
- Obstructive sleep apnea (OSA) is frequently linked to pulmonary hypertension.
- This association often leads to a poorer prognosis if left untreated.
- However, OSA-associated pulmonary hypertension is underrecognized by clinicians.
Purpose of the Study:
- To review the prevalence of pulmonary hypertension in OSA patients.
- To explore the pathophysiology, clinical presentation, and treatment options.
- To discuss the prognosis of this condition.
Main Methods:
- This is a review article.
- Information was gathered from existing literature on OSA and pulmonary hypertension.
Main Results:
- Pulmonary hypertension prevalence in OSA ranges from 17% to 53%.
- The pathophysiology is complex and not fully understood.
- Continuous positive airway pressure (CPAP) is effective in treating OSA-associated pulmonary hypertension.
Conclusions:
- OSA-associated pulmonary hypertension is a significant clinical issue.
- Further research is needed for a better understanding of this disease entity.
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