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Updated: Feb 25, 2026

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis
Published on: November 22, 2024
Carotid Stenosis and Impaired Cognition: The Effect of Intervention
1From the *Stony Brook University School of Medicine, Stony Brook, NY; †Division of Vascular Surgery, Winthrop University Hospital, Mineola, NY.
Abstract:
There is a clear association between carotid artery stenosis and cognitive impairment. However, there is no consensus as to how to interpret this association, and what, if any, impact this connection should have on the management of carotid stenosis. A review of the relevant literature suggests that although an intervention to relieve carotid stenosis in patients without clinically significant cognitive impairment does not improve cognition, there may be a cognitive benefit with intervention for carotid stenosis in those patients with clinically significant cognitive disorders.
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