Related Experiment Video
Updated: Feb 25, 2026

09:04
A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
Published on: September 9, 2016
11.2K
Auramine-o (Synthetic Yellow Cow Dung Powder) Poisoning: Rare but Fatal
Shubhangi Dhadke1, Vitthal Dhadke2, Abhijit Giram3
1Associate Professor.
The Journal of the Association of Physicians of India
|August 10, 2017
Summary
Synthetic yellow cow dung powder (Auramine-o) poisoning is a rare condition, primarily affecting young females. Prompt symptomatic treatment leads to low mortality rates in these cases.
Area of Science:
- Toxicology
- Public Health
Background:
- Traditional use of cow dung for its germicidal properties.
- Increasing use of synthetic yellow cow dung powder (Auramine-o) as a substitute.
- Limited literature on Auramine-o poisoning mechanisms, presentation, and complications.
Purpose of the Study:
- To investigate the clinical features, treatment strategies, and outcomes of synthetic yellow cow dung powder poisoning.
Main Methods:
- Study included 25 patients with confirmed Auramine-o poisoning.
- Routine investigations included blood sugar level (BSL), renal function tests (RFT), and liver function tests (LFT).
- CT brain imaging was performed when clinically indicated.
Main Results:
- Poisoning predominantly affected young individuals, particularly females.
- Common symptoms included vomiting and respiratory depression.
- Treatment primarily involved symptomatic management.
Conclusions:
- Synthetic yellow cow dung powder poisoning is rare, with a low mortality rate when managed promptly.
- Symptomatic treatment is the mainstay for Auramine-o poisoning.
- Further research may be needed to fully understand long-term effects.
Related Concept Videos
Physical Properties of Amines
4.3K
Amines with low molecular weight are usually gaseous at room temperature, while those with high molecular weight are liquid or solids in nature. Usually, low molecular weight amines have a rotten fish-like smell. Diamines typically have a pungent smell. For instance, cadaverine and putrescine, depicted in Figure 1, are two molecules responsible for decaying tissue.
4.3K
Pharmaceutical Poisoning: Treatment Strategies
55
Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...
55
Anticholinesterase Agents: Poisoning and Treatment
1.8K
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
1.8K
Prevention of Further Absorption of Poison
1.3K
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.3K
Lethal Alleles
18.4K
Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
18.4K
Antidotes
1.2K
Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely designed to combat specific toxic compounds.
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
1.2K

