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Published on: May 6, 2013
Listeria in Adults - Truly Rare or Rarely Diagnosed in India?
Arjun Rajalakshmi1, Ram Gopalakrishnan2, P Senthur Nambi3
1Fellow.
Abstract:
Listeria monocytogenes is a facultative anaerobic intracellular Gram positive rod causing infection in pregnant women, extremes of age and immune-compromised hosts. In clinical specimens, the organisms may be gram-variable: laboratory misidentification of L. monocytogenes isolates as diphtheroids, streptococci, or enterococci is not uncommon and the isolation of a diphtheroid from blood or CSF should always alert the clinician to the possibility that the organism may be L. monocytogenes. The disease has rarely been reported in India in non-pregnant adults. We herein report four cases of L. monocytogenes infection in immune-compromised adults.
Insights
Listeria monocytogenes infections are rare in non-pregnant Indian adults. This report details four cases of Listeria monocytogenes infection in immunocompromised adults, highlighting diagnostic challenges.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Medicine
Background:
- Listeria monocytogenes is a Gram-positive bacterium causing infections in vulnerable populations.
- Misidentification of Listeria monocytogenes in clinical samples can occur, potentially delaying diagnosis.
- Listeriosis is infrequently reported in non-pregnant adults in India.
Observation:
- This study reports four cases of Listeria monocytogenes infection.
- The cases involved immunocompromised adult patients.
- The clinical presentation and diagnostic considerations are discussed.
Findings:
- Listeria monocytogenes can cause severe infections in immunocompromised adults.
- Laboratory identification challenges may lead to misdiagnosis.
- Early recognition is crucial for effective treatment.
Implications:
- Clinicians should consider Listeria monocytogenes in immunocompromised patients, especially if diphtheroids are suspected in blood or CSF.
- Increased awareness and improved diagnostic methods are needed for Listeria monocytogenes detection.
- This case series contributes to understanding listeriosis epidemiology in India.
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