Feline cutaneous histoplasmosis: The first case report from Thailand

L Larsuprom1, L Duangkaew1, C Kasorndorkbua2

  • 1Dermatology Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Kasetsart University, Thailand.

Insights

Feline histoplasmosis, a fungal infection caused by Histoplasma capsulatum, was diagnosed in a domestic shorthaired cat in Thailand. This case highlights the potential for this rare disease in felines and its presentation in a new geographic region.

Area of Science:

  • Veterinary Mycology
  • Feline Infectious Diseases

Background:

  • Histoplasmosis is a systemic fungal infection caused by Histoplasma capsulatum.
  • Feline histoplasmosis is rare and typically presents with disseminated disease.
  • Cutaneous manifestations can occur but are less common.

Purpose of the Study:

  • To report the first case of feline cutaneous histoplasmosis in Thailand.
  • To describe the clinical and histopathological findings of this rare condition in a cat.
  • To confirm the diagnosis using molecular methods.

Main Methods:

  • Clinical examination and history taking.
  • Skin biopsy and histopathological examination.
  • Polymerase Chain Reaction (PCR) for Histoplasma capsulatum identification.

Main Results:

  • A 2-year-old cat presented with multiple skin lesions including papules, nodules, and a chronic wound.
  • Histopathology revealed yeasts within macrophages in the skin.
  • PCR confirmed the presence of Histoplasma capsulatum DNA.

Conclusions:

  • This is the first documented case of feline cutaneous histoplasmosis in Thailand.
  • The findings suggest that Histoplasma capsulatum should be considered in the differential diagnosis of feline skin lesions, even in previously unreported regions.
  • Early diagnosis and treatment are crucial for managing feline histoplasmosis.

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