Related Experiment Video
Updated: Jul 31, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
Feline cutaneous histoplasmosis: The first case report from Thailand
L Larsuprom1, L Duangkaew1, C Kasorndorkbua2
1Dermatology Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Kasetsart University, Thailand.
Abstract:
A 2-year-old, neutered female domestic shorthaired cat presented with a history of multiple papules and nodules on pinnae, nodules on the nose, and chronic wound at the lateral surface of left radial area for four months. Skin biopsy demonstrated moderate numbers of small, oval-to-round, single-walled yeasts inside the macrophages. In addition, PCR confirmed the sequence of Histoplasma capsulatum. This is the first case report of feline cutaneous histoplasmosis in Thailand.
Insights
Feline histoplasmosis, a fungal infection caused by Histoplasma capsulatum, was diagnosed in a domestic shorthaired cat in Thailand. This case highlights the potential for this rare disease in felines and its presentation in a new geographic region.
Area of Science:
- Veterinary Mycology
- Feline Infectious Diseases
Background:
- Histoplasmosis is a systemic fungal infection caused by Histoplasma capsulatum.
- Feline histoplasmosis is rare and typically presents with disseminated disease.
- Cutaneous manifestations can occur but are less common.
Purpose of the Study:
- To report the first case of feline cutaneous histoplasmosis in Thailand.
- To describe the clinical and histopathological findings of this rare condition in a cat.
- To confirm the diagnosis using molecular methods.
Main Methods:
- Clinical examination and history taking.
- Skin biopsy and histopathological examination.
- Polymerase Chain Reaction (PCR) for Histoplasma capsulatum identification.
Main Results:
- A 2-year-old cat presented with multiple skin lesions including papules, nodules, and a chronic wound.
- Histopathology revealed yeasts within macrophages in the skin.
- PCR confirmed the presence of Histoplasma capsulatum DNA.
Conclusions:
- This is the first documented case of feline cutaneous histoplasmosis in Thailand.
- The findings suggest that Histoplasma capsulatum should be considered in the differential diagnosis of feline skin lesions, even in previously unreported regions.
- Early diagnosis and treatment are crucial for managing feline histoplasmosis.
Related Concept Videos
Rocky Mountain Spotted Fever
Hepatitis
Toxoplasmosis
American Trypanosomiasis

