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Three Complete Genome Sequences of Genotype G Mumps Virus from the 2016 Outbreak in Arkansas, USA

Duah Alkam1, Thidathip Wongsurawat1, Piroon Jenjaroenpun1

  • 1Department of Biomedical Informatics, College of Medicine, The University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Genome Announcements
|August 12, 2017
PubMed

Insights

Researchers sequenced three mumps virus (MuV) genomes from a 2016 outbreak in Arkansas. The complete genome sequences belong to genotype G, providing insights into mumps virus evolution and epidemiology.

Area of Science:

  • Virology
  • Genomics
  • Epidemiology

Background:

  • Mumps virus (MuV) causes contagious respiratory illness.
  • Outbreaks continue to occur globally, necessitating genomic surveillance.

Purpose of the Study:

  • To present the complete genome sequences of three MuV strains from a 2016 outbreak in Springdale, AR.
  • To characterize these strains based on their genomic data.

Main Methods:

  • Whole genome sequencing of MuV strains using Oxford Nanopore technology.
  • Bioinformatic analysis of obtained genome sequences.

Main Results:

  • Complete genome sequences of three MuV strains were obtained.
  • The average genome length was 15,342 nucleotides.
  • All sequenced strains belonged to genotype G.

Conclusions:

  • The genomic data provides valuable information for understanding the epidemiology of mumps virus.
  • Sequencing of MuV strains aids in tracking viral evolution and informing public health responses.

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