Related Experiment Video
Updated: Feb 24, 2026
05:14
Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
1.6K
MACROANEURYSMS ASSOCIATED WITH CONGENITAL RETINAL MACROVESSELS
Dov B Sebrow1,2,3,4, Eduardo Cunha de Souza5, José Belúcio Neto5
1Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York.
Retinal Cases & Brief Reports
|August 12, 2017
Summary
Congenital retinal macrovessels with macroaneurysms can affect vision but may resolve with observation. Optical coherence tomography angiography is key to visualizing these vascular anomalies.
Area of Science:
- Ophthalmology
- Vascular Biology
- Medical Imaging
Background:
- Congenital retinal macrovessels are rare, aberrant blood vessels crossing the horizontal raphe and potentially involving the macula.
- Macroaneurysms are localized dilations of retinal vessels, which can be arterial or venous.
Observation:
- Two cases of congenital retinal macrovessels associated with macroaneurysms were evaluated using multimodal imaging.
- Advanced imaging techniques including optical coherence tomography angiography (OCTA) were employed to visualize the vascular structures and capillary networks.
Findings:
- One patient presented with vision loss due to a ruptured venous macrovessel macroaneurysm and microaneurysms, showing improvement after 3 months.
- The second patient had an incidental finding of an arterial macrovessel with an associated macroaneurysm.
- Both cases revealed complex macular capillary networks visualized by OCTA.
Implications:
- Macroaneurysms can occur on both arterial and venous congenital retinal macrovessels.
- Ruptured macroaneurysms with associated hemorrhage and exudation may resolve with conservative management.
- Optical coherence tomography angiography is crucial for diagnosing and monitoring these complex vascular anomalies and their associated capillary networks.
