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Updated: Feb 24, 2026

A Non-Coding Small RNA MicC Contributes to Virulence in Outer Membrane Proteins in Salmonella Enteritidis
Published on: January 27, 2021
MicroRNA mediated regulation of immunity against gram-negative bacteria
Jonathon Keck1, Rishein Gupta1, Lane K Christenson2
1a South Texas Center for Emerging Infectious Diseases and Center of Excellence in Infection Genomics , University of Texas at San Antonio , One UTSA Circle, San Antonio , TX.
Abstract:
Evidence over the last couple decades has comprehensively established that short, highly conserved, non-coding RNA species called microRNA (miRNA) exhibit the ability to regulate expression and function of host genes at the messenger RNA (mRNA) level. MicroRNAs play key regulatory roles in immune cell development, differentiation, and protective function. Intrinsic host immune response to invading pathogens rely on intricate orchestrated events in the development of innate and adaptive arms of immunity. We discuss the involvement of miRNAs in regulating these processes against gram negative pathogens in this review.
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