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Updated: Feb 24, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
[Interpretation of the Intraocular Lens Constants for the Haigis Formula]
Simon Schröder1, Stefan Wagenpfeil2, Christina Leydolt3
1Experimentelle Ophthalmologie, Universität des Saarlandes, Homburg/Saar.
Abstract:
Background The Haigis formula uses a linear regression with three IOL constants for the prediction of the effective lens position (ELP) of the intraocular lens (IOL), ELP ≈ a0 + a1 ACD + a2 L. It is based on the preoperative anterior chamber depth (ACD) and axial length (L). Material and Methods Differences between IOL constant triplets can be judged based on their statistical measurement uncertainty. To investigate, if the estimation of the average ELP with the help of the average ACD and average L according to 〈ELP〉 ≈ a0 + a1 〈ACD〉 + a2 〈L〉 provides a possible alternative, we have compared both methods. The results based on two different strategies for optimisation of the IOL constants a0, a1, a2 are used for illustration. Results The estimation of the average ELP is suitable for basic categorisation of the IOL constants. The confidence-volumes in shape of ellipsoids based on the statistical measurement uncertainties of the IOL constant optimisations allow a better comparison between IOL constant triplets a0, a1, a2.
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