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Updated: Jul 12, 2026

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Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
Published on: August 23, 2011
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Dynamic Three-Dimensional Geometry of the Aortic Valve Apparatus-A Feasibility Study
Arash Khamooshian1, Yannis Amador2, Ting Hai3
1Department of Cardio-Thoracic Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Journal of Cardiothoracic and Vascular Anesthesia
|August 13, 2017
Summary
The aortic valve apparatus is dynamic, with significant changes in geometry during the cardiac cycle. This 3D TEE analysis using eSie valve software is feasible for intraoperative assessment.
Area of Science:
- Cardiovascular Imaging
- Cardiac Surgery
- Echocardiography
Background:
- The aortic valve (AV) apparatus is crucial for cardiac function.
- Understanding its normal anatomy and dynamic behavior is essential for surgical interventions.
- Three-dimensional transesophageal echocardiography (3D TEE) offers detailed visualization.
Purpose of the Study:
- To present the anatomy and nomenclature of the aortic valve apparatus.
- To provide data on normal AV apparatus geometry and dynamics during the cardiac cycle using 3D TEE.
Main Methods:
- Retrospective feasibility study involving 10 patients with normal aortic valves undergoing surgery.
- Intraoperative 3D TEE was performed using Siemens ACUSON SC2000.
- Semiautomated dynamic analysis of the AV apparatus using Siemens eSie valve software.
Main Results:
- Significant changes in AV apparatus dimensions (annulus, sinus of Valsalva, sinotubular junction) and leaflet coaptation occurred during the cardiac cycle (p < 0.001).
- The sinotubular junction exhibited greater expansion than the annulus and sinus of Valsalva (p < 0.001).
- Leaflet height changes varied between leaflets, with left and right coronary leaflets showing greater changes.
Conclusions:
- Semiautomated dynamic assessment of the AV apparatus with eSie valve software is clinically feasible in the operating room.
- This technique can aid intraoperative decision-making for aortic valve repair.
- The aortic valve apparatus is a dynamic structure with significant cardiac cycle-dependent geometric alterations.

