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Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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Updated: Feb 24, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Alternating trifascicular block and cardiac memory.

Asaf Danon1, Mohammed Shurrab2

  • 1Department of Cardiology, Carmel Medical Center, Haifa, Israel.

Journal of Electrocardiology
|August 14, 2017
PubMed
Summary
This summary is machine-generated.

A 70-year-old woman experienced worsening atrioventricular (AV) block with exercise due to an alternating trifascicular conduction pattern. This case highlights T wave memory changes and strategies for managing exercise-induced AV block.

Keywords:
Alternating blockAtrioventricular blockExercise induced AV blockT wave memory

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Internal Medicine

Background:

  • Atrioventricular (AV) block is a condition affecting the heart's electrical signaling.
  • Trifascicular conduction patterns can predispose individuals to complex arrhythmias.
  • Exercise can unmask or exacerbate underlying cardiac conduction abnormalities.

Observation:

  • A 70-year-old woman presented with dyspnea on exertion and an alternating trifascicular conduction pattern.
  • The conduction pattern worsened during exercise, leading to atrioventricular block.
  • At rest, the alternating conduction was associated with significant T wave abnormalities.

Findings:

  • The case demonstrates exercise-induced atrioventricular block secondary to an alternating trifascicular conduction pattern.
  • T wave memory changes were observed, linked to the dynamic alterations in cardiac conduction.
  • The interplay between conduction system disease and exertion-related hemodynamic changes is highlighted.

Implications:

  • Understanding T wave memory mechanisms is crucial for diagnosing and managing conduction disorders.
  • Effective management strategies for exercise-induced AV block are essential for patient prognosis.
  • This case underscores the importance of thorough cardiac evaluation in patients with exertional symptoms and conduction abnormalities.