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Updated: Feb 24, 2026
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Optical Coherence Tomography Angiography in Children with Leber-Coats Disease
Michele Fortunato1, Angela Turtoro, Gilda Cennamo
1Ospedale Pediatrico Bambino Gesù, Rome, Italy.
Introduction:
The aim of this work was to describe the optical coherence tomography (OCT) angiography (OCTA) features in paediatric Leber-Coats disease.
Methods:
Three children presenting with unilateral, clinically active Leber-Coats disease were evaluated using spectral domain OCT and OCTA. OCT angiograms were analysed and compared with the current literature.
Results:
All 3 OCT angiograms showed that the vessels had lost most of their collateral branches and presented many loops. The capillaries were rarefied and anomalies in vessel size, vasodilatation, and macroaneurysms were evident.
Conclusion:
This is the first case series of OCTA performed in children with Leber-Coats disease. OCTA is a non-invasive and non-contact technique, which can be considered of fundamental importance for the diagnosis, clinical management, and follow-up of the disease.
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