Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gross Anatomy of the Lungs01:17

Gross Anatomy of the Lungs

5.2K
The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
5.2K
Development of Blood Vessels01:07

Development of Blood Vessels

1.6K
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

YAP1 drives aggressive and therapy resistant state in melanoma through reprogramming the chromatin and regulating immune evasive programs.

bioRxiv : the preprint server for biology·2025
Same author

A latent Axin2<sup>+</sup>/Scx<sup>+</sup> progenitor pool is the central organizer of tendon healing.

NPJ Regenerative medicine·2024
Same author

Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing.

Nature communications·2024
Same author

Airway basal stem cells are necessary for the maintenance of functional intraepithelial airway macrophages.

bioRxiv : the preprint server for biology·2024
Same author

Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.

Nature·2024
Same author

A deep lung cell atlas reveals cytokine-mediated lineage switching of a rare cell progenitor of the human airway epithelium.

bioRxiv : the preprint server for biology·2023
Same journal

Restraint of melanoma progression by cells in the local skin environment.

eLife·2026
Same journal

Brawn before bite in endemic Asian eutherian mammals after the end-Cretaceous extinction.

eLife·2026
Same journal

Experimental evolution to thermal stress indicates climate resilience in a cosmopolitan arthropod.

eLife·2026
Same journal

Correlates of protection against African swine fever virus identified by a systems immunology approach.

eLife·2026
Same journal

Retrosplenial cortex enables context-dependent goal-directed sensorimotor transformation.

eLife·2026
Same journal

Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation.

eLife·2026
See all related articles

Related Experiment Video

Updated: Feb 24, 2026

Mouse Embryonic Lung Culture, A System to Evaluate the Molecular Mechanisms of Branching
07:32

Mouse Embryonic Lung Culture, A System to Evaluate the Molecular Mechanisms of Branching

Published on: June 30, 2010

19.0K

Tips from the embryonic lung.

Avinash Waghray1, Jayaraj Rajagopal1

  • 1Massachusetts General Hospital, Harvard University, Boston, United States.

Elife
|August 15, 2017
PubMed
Summary
This summary is machine-generated.

Researchers have discovered a novel progenitor cell source to investigate human lung development and pediatric lung diseases. This breakthrough offers new insights into complex respiratory conditions affecting children.

Keywords:
alveolar differentiationbranchingdevelopmental biologyhumanhuman biologylung developmentmedicineorgan developmentstem cellstem cellstip progenitor

More Related Videos

Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease
09:45

Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease

Published on: April 12, 2021

9.4K
Procedure for Lung Engineering
12:50

Procedure for Lung Engineering

Published on: March 8, 2011

47.4K

Related Experiment Videos

Last Updated: Feb 24, 2026

Mouse Embryonic Lung Culture, A System to Evaluate the Molecular Mechanisms of Branching
07:32

Mouse Embryonic Lung Culture, A System to Evaluate the Molecular Mechanisms of Branching

Published on: June 30, 2010

19.0K
Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease
09:45

Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease

Published on: April 12, 2021

9.4K
Procedure for Lung Engineering
12:50

Procedure for Lung Engineering

Published on: March 8, 2011

47.4K

Area of Science:

  • Pulmonology
  • Developmental Biology
  • Stem Cell Research

Background:

  • Understanding human lung development is crucial for addressing pediatric lung diseases.
  • Previous research faced limitations in accessing relevant cellular models.

Purpose of the Study:

  • To introduce and validate a new progenitor cell source for studying human lung development.
  • To explore previously inaccessible aspects of pediatric lung disease pathogenesis.

Main Methods:

  • Isolation and characterization of novel progenitor cells.
  • In vitro and in vivo models of lung development and disease.

Main Results:

  • The new progenitor cells successfully recapitulate key aspects of human lung development.
  • These cells provide a platform to model specific pediatric lung pathologies.

Conclusions:

  • A new progenitor cell source offers unprecedented opportunities for respiratory research.
  • This discovery is expected to advance the understanding and treatment of pediatric lung conditions.