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Rare Ileal Ewing Sarcoma/Primitive Neuroectodermal Tumor on 18F-FDG PET/CT
Pan Yu1, Fei Xiaochun, Lv Jing
1From the Departments of *Nuclear Medicine, and †Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Clinical Nuclear Medicine
|August 15, 2017
Summary
A rare ileal Ewing sarcoma presented as anemia and a small intestinal lump in a young woman. Surgical resection confirmed the diagnosis, highlighting the importance of considering rare tumors in differential diagnoses.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Microcytic hypochromic anemia, melena, dizziness, and fatigue are common presenting symptoms.
- Splenomegaly and small intestinal lesions require thorough investigation.
Observation:
- Enhanced CT revealed an ileal lesion with contrast enhancement.
- Positron Emission Tomography/Computed Tomography (PET/CT) showed increased Fluorodeoxyglucose (FDG) uptake in the ileal lesion.
- Initial suspicion was directed towards lymphoma based on imaging findings.
Findings:
- Histopathologic and immunohistochemical examination confirmed the ileal lesion as a rare Ewing sarcoma/primitive neuroectodermal tumor.
- The patient underwent uncomplicated surgical resection of the ileal lesion.
Implications:
- This case underscores the importance of considering rare small intestinal tumors in the differential diagnosis of unexplained anemia and abdominal masses.
- Accurate diagnosis relies on a combination of advanced imaging and definitive histopathological analysis.
- Early detection and surgical management are crucial for favorable outcomes in rare pediatric-type sarcomas presenting in adults.

