Related Experiment Video
Updated: Feb 24, 2026

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools
Published on: November 11, 2020
SAXS4COLL: an integrated software tool for analysing fibrous collagen-based tissues
Ahmed Abass1, James S Bell1, Martin T Spang1
1Structural Biophysics Group, School of Optometry and Vision Science, Cardiff University, Maindy Road, Cardiff CF24 4HQ, UK.
None:
This article provides an overview of a new integrated software tool for reduction and analysis of small-angle X-ray scattering (SAXS) data from fibrous collagen tissues, with some wider applicability to other cylindrically symmetric scattering systems. SAXS4COLL combines interactive features for data pre-processing, bespoke background subtraction, semi-automated peak detection and calibration. Both equatorial and meridional SAXS peak parameters can be measured, and the former can be deconstructed into cylinder and lattice contributions. Finally, the software combines functionality for determination of collagen spatial order parameters with a rudimentary orientation plot capability.

