Related Experiment Video
Updated: Feb 24, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform
Massimo Nicolò1,2, Monica Bonetto3, Raffaella Rosa1
1Clinica Oculistica-DINOGMI, Università di Genova and Italy Ospedale Policlinico San Martino, Genoa, Italy.
Aim:
Real-life evaluation in the management of patients affected by macular edema secondary to retinal vein occlusion.
Material And Methods:
A retrospective, observational study using the I-Macula Web platform.
Results:
Thirty-five patients (37 eyes; 15 females and 20 male) affected by RVO were analysed. At 12 months, there was a statistically significant improvement of best-corrected visual acuity (p = 0.0235) and central macular thickness (p < 0.0001). The mean change in visual acuity was 8.9 letters. Twenty-seven eyes underwent DEX implant (n = 62; mean: 2.29) only. Of these, 8, 4, 14, and 1 eyes underwent 1, 2, 3, and 4 DEX implants, respectively. The remaining 10 eyes were also injected with ranibizumab (n = 49; mean: 4.9). At 12 months, 12 eyes (32.5%) presented a dry macula, whereas the remaining 25 eyes (67.5%) still had macular edema. Mean interval between the first and second treatment (T1) and between the second and third treatment (T2) were 5.15 and (T2) 3.7 months, respectively. Where only DEX implants were received, T1 and T2 was 5.1 and 4.9 months, respectively.
Conclusions:
This study confirms that DEX implants and/or anti-VEGF drugs improve visual acuity and central macular thickness in patients affected by RVO.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Peripheral Artery Disease IV: Nursing Management
Mitral Stenosis III: Medical Management

