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Updated: Feb 24, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Comparing glaucomatous disc change using stereo disc viewing and the MatchedFlicker programme in glaucoma experts and
Jamie L Schaefer1,2, Alissa M Meyer1, Cooper D Rodgers1
1Department of Ophthalmology, University of Florida, Gainesville, Florida, USA.
The MatchedFlicker software improves the speed and accuracy of detecting glaucomatous optic disc changes compared to manual stereoscopic viewing. Both glaucoma specialists and trainees benefit from this digital tool.
Area of Science:
- Ophthalmology
- Medical Imaging
- Glaucoma Diagnosis
Background:
- Glaucomatous optic disc change detection is crucial for timely intervention.
- Manual examination of stereoscopic disc photographs is a standard but time-consuming method.
- Evaluating new tools to enhance diagnostic efficiency is essential.
Purpose of the Study:
- To compare the accuracy and speed of MatchedFlicker software versus manual stereoscopic viewing for glaucoma detection.
- To assess performance differences between trainees and experienced glaucoma specialists.
Main Methods:
- 140 image pairs from 100 eyes were evaluated by glaucoma specialists and trainees.
- Evaluators used both a handheld stereo viewer and MatchedFlicker software.
- Accuracy and evaluation time were measured for each method.
Main Results:
- MatchedFlicker software was 26% faster per image pair (p=0.0007) and improved accuracy (p=0.0003).
- No significant speed or accuracy differences were found between expert and trainee groups.
- Experts showed higher consistency with duplicate images (p=0.029), while trainees were more conservative in diagnosing progression.
Conclusions:
- MatchedFlicker software offers superior accuracy and speed for glaucoma diagnosis compared to traditional stereoscopic viewers.
- The software benefits both experienced specialists and trainees in ophthalmology.
- Digital tools can enhance the efficiency of glaucoma detection.
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