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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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Pulmonary Embolism III: Nursing Management01:27

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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
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Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Related Experiment Video

Updated: Feb 24, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Amniotic fluid embolism mortality rate.

Michael D Benson1

  • 1Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

The Journal of Obstetrics and Gynaecology Research
|August 18, 2017
PubMed
Summary
This summary is machine-generated.

The maternal mortality rate from amniotic fluid embolism (AFE) is approximately 20.4%, based on large population studies. Case series data are unreliable for determining AFE lethality.

Keywords:
amniotic fluid embolismcase seriesmaternal mortalitymaternal mortality ratepopulation-based study

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Area of Science:

  • Obstetrics and Gynecology
  • Perinatal Medicine
  • Critical Care Medicine

Background:

  • Amniotic fluid embolism (AFE) is a rare but catastrophic obstetric emergency.
  • Accurate estimation of AFE mortality is crucial for clinical risk assessment and public health planning.

Purpose of the Study:

  • To determine the population-based mortality rate of amniotic fluid embolism (AFE).
  • To evaluate the reliability of case series data in reporting AFE mortality.

Main Methods:

  • A comprehensive literature search was performed using keywords 'amniotic fluid embolism' and 'mortality rate'.
  • Population-based studies and case series reporting AFE were systematically evaluated.
  • Data from nine population-based studies encompassing over 17 million live births were aggregated.

Main Results:

  • Mortality rates in population-based studies ranged from 11% to 44%.
  • Aggregated data from nine large population-based studies indicated a maternal mortality rate of 20.4% for AFE.
  • Case series reported highly variable AFE mortality rates (0% to 100%), highlighting data limitations.

Conclusions:

  • The most reliable estimate for amniotic fluid embolism (AFE) mortality, derived from population-based studies, is 20.4%.
  • Findings strongly suggest that case series data are inappropriate for characterizing the lethality of AFE.
  • This study provides a more accurate mortality figure for AFE, essential for clinical and public health contexts.