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3D imaging of optically cleared tissue using a simplified CLARITY method and on-chip microscopy

Yibo Zhang1,2,3, Yoonjung Shin2,4, Kevin Sung2,4

  • 1Electrical Engineering Department, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Science Advances
|August 19, 2017
PubMed
Summary

We developed a low-cost, high-throughput 3D imaging technique for optically cleared tissues using lens-free holographic microscopy. This method offers a simple and data-efficient alternative for biomedical research and diagnosis, especially in resource-limited settings.

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