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Updated: Feb 24, 2026
Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization
Published on: May 15, 2018
Enumeration, Dielectrophoretic Capture, and Molecular Analysis of Circulating Tumor Cells
Stephanie S Yee1, Erica L Carpenter2
1Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, #8-104, South Pavilion, 8th Fl., 3400 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Abstract:
The identification of therapeutically targetable mutations in circulating tumor cells (CTCs) from cancer patient blood is increasingly used to personalize patient care. Here, we describe a novel approach for the enumeration, capture, and molecular analysis of CTCs from blood using an FDA-approved CTC enrichment and enumeration platform followed by dielectrophoretic capture and next-generation sequencing.
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