Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

14.2K
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
14.2K
Bone Disorders01:29

Bone Disorders

5.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.7K
Spinal Nerves: Anatomy01:23

Spinal Nerves: Anatomy

9.7K
Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
9.7K
Bones of the Upper Limb: Radius01:09

Bones of the Upper Limb: Radius

10.5K
The radius is longer of the two bones that make up the human antebrachium or forearm. At the proximal end, the radius articulates with the capitulum of the humerus and the radial notch of the ulna to form the elbow joint. At the distal end, the radius articulates with the ulna via the ulnar notch, forming the distal radioulnar joint. Distally, the radius also attaches to the carpal wrist bones (scaphoid and lunate) to form the radiocarpal joint.
The radius has a nail-shaped head, and a...
10.5K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

4.4K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
4.4K
Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

11.0K
The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
11.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simultaneous Oblique Lumbar Interbody Fusion and Percutaneous Pedicle Screw Fixation Combined With Endoscopic-Assisted Decompression in the Lateral Position for Two-Level Lumbar Pathology.

Cureus·2026
Same author

Comparison of Surgical Outcomes Between Vertebral Body Stenting (VBS) and Balloon Kyphoplasty (BKP)-Multicenter Cohort Study.

Journal of clinical medicine·2026
Same author

Radiographic subsidence after single-level anterior cervical discectomy and fusion; a comparison between blade-anchored zero-profile cages and stand-alone cages.

Journal of orthopaedic surgery and research·2026
Same author

Cerium isotopes unveil hydrogenetic Fe-Mn encrustation occurring throughout from the oxygen minimum zone to the deep pacific.

Science advances·2026
Same author

A novel C-Arm-free navigation-guided endoscopy-assisted extraforaminal decompression for L5 radiculopathy with far-out syndrome: a surgical technical note.

Journal of spine surgery (Hong Kong)·2026
Same author

Distance to junction and small saphenous vein treatment drive risk of ≥grade 2 endothermal heat-induced thrombosis in multicenter practice.

Journal of vascular surgery. Venous and lymphatic disorders·2026
Same journal

Determination of the Side Responsible for Bilateral Pneumothorax due to Pleural Communication.

Acta medica Okayama·2026
Same journal

Common Bile Duct Stone Formed Around an Ingested Fish Bone.

Acta medica Okayama·2026
Same journal

A Novel Flap Design to Reduce Urethral Complications in Anterolateral Thigh Phalloplasty: The Pipe Flap Technique.

Acta medica Okayama·2026
Same journal

Evaluation of Bone Mineral Density and Bone Structure in the Cervical and Thoracic Spine.

Acta medica Okayama·2026
Same journal

HIP COMPASS®: A Mechanical Intraoperative Navigation Guide Associated with Improved Revision-Free Implant Survivorship after Ceramic-on-Ceramic Total Hip Arthroplasty at Minimum 10-Year Follow-up.

Acta medica Okayama·2026
Same journal

Reducing Hesitation in Resuscitation: Educational Effects of a Female-Appearing Simulator in Basic Life Support Training.

Acta medica Okayama·2026
See all related articles

Related Experiment Video

Updated: Feb 24, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model
06:11

Anterior Cervical Discectomy and Fusion in the Ovine Model

Published on: October 5, 2009

13.3K

Cervical Spine Osteoradionecrosis.

Masato Tanaka1, Yoshihisa Sugimoto, Tomoyuki Takigawa

  • 1Department of Orthopaedic Surgery, Okayama University Hospital, Okayama 700-8558, Japan.tanakam@md.okayama-u.ac.jp.

Acta Medica Okayama
|August 22, 2017
PubMed
Summary
This summary is machine-generated.

Osteoradionecrosis of the cervical spine is a rare but serious complication of radiotherapy. Early diagnosis and surgical reconstruction are crucial for successful treatment and preserving spinal alignment.

Keywords:
cervical spinelaryngeal carcinomaosteoradionecrosisradiotherapy

More Related Videos

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity
06:45

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity

Published on: September 16, 2022

2.9K

Related Experiment Videos

Last Updated: Feb 24, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model
06:11

Anterior Cervical Discectomy and Fusion in the Ovine Model

Published on: October 5, 2009

13.3K
Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity
06:45

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity

Published on: September 16, 2022

2.9K

Area of Science:

  • Oncology
  • Orthopedic Surgery
  • Radiotherapy

Background:

  • Osteoradionecrosis (ORN) is a known complication of radiotherapy, typically affecting the mandible.
  • ORN of the cervical spine is exceptionally rare.

Observation:

  • A 63-year-old female patient with a history of laryngeal carcinoma treated with 120 Gy radiotherapy developed severe neck pain 8 years later.
  • The patient was diagnosed with cervical spine osteoradionecrosis.

Findings:

  • Surgical reconstruction using vascularized fibular bone graft and posterior pedicle screw fixation successfully preserved cervical alignment.
  • The patient experienced no neurological deficits and minimal neck pain at a 3-year follow-up.

Implications:

  • Early diagnosis of cervical spine ORN is critical due to potential life-threatening complications.
  • Otolaryngologists and spine surgeons must be aware of this rare complication to facilitate prompt diagnosis and treatment.