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Cutaneous changes associated with inflammatory bowel disease.

A S Paller

    Pediatric Dermatology
    |December 1, 1986
    PubMed
    Summary
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    Inflammatory bowel disease (IBD) can manifest with skin lesions, sometimes preceding gastrointestinal symptoms. While IBD treatment may improve skin conditions, additional therapies might be necessary.

    Area of Science:

    • Gastroenterology
    • Dermatology
    • Pediatrics

    Background:

    • Inflammatory bowel disease (IBD) commonly affects adolescents but can occur in younger children.
    • Skin manifestations are frequent complications of IBD.
    • Cutaneous changes can sometimes be the initial clinical presentation of IBD.

    Purpose of the Study:

    • To review the spectrum of skin lesions associated with inflammatory bowel disease.
    • To highlight the diagnostic and therapeutic implications of cutaneous manifestations in IBD.
    • To discuss management strategies for IBD-related dermatoses.

    Main Methods:

    • Literature review of studies on IBD and associated skin conditions.
    • Analysis of case reports and clinical series detailing dermatological findings in IBD patients.

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  • Synthesis of current understanding regarding pathogenesis and treatment.

    • Main Results:

    • Erythema nodosum and pyoderma gangrenosum are the most prevalent specific skin changes.
    • A wide array of other dermatoses can be associated with IBD.
    • Skin lesions may precede, coincide with, or follow the diagnosis of IBD.

    Conclusions:

    • Cutaneous manifestations are an important consideration in the comprehensive management of IBD.
    • Treatment of the underlying bowel disease often improves skin lesions.
    • Refractory or specific skin conditions may necessitate independent dermatological treatment.