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Updated: Feb 24, 2026

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Production, Crystallization and Structure Determination of C. difficile PPEP-1 via Microseeding and Zinc-SAD
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Complete genome sequence of Peptoclostridium difficile strain Z31
Felipe L Pereira1, Carlos A Oliveira Júnior2, Rodrigo O S Silva2
1National Reference Laboratory for Aquatic Animal Diseases (AQUACEN), Ministry of Fisheries and Aquaculture, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Gut Pathogens
|August 23, 2017
Summary
The genome of nontoxigenic Peptoclostridium difficile strain Z31 was sequenced, revealing genes for spore stability and adherence. This strain shows potential for preventing C. difficile infections as a competitive exclusion agent.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Peptoclostridium difficile causes significant nosocomial infections in humans and animals.
- No effective vaccines or treatments are currently available for C. difficile infections.
- Nontoxigenic C. difficile strains are being investigated as potential competitive exclusion agents.

