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Nanocellulosic materials as bioinks for 3D bioprinting
Carmen C Piras1, Susana Fernández-Prieto, Wim M De Borggraeve
1Molecular Design and Synthesis, Department of Chemistry, KU Leuven - University of Leuven, Celestijnenlaan 200F, box 2404, B-3001 Leuven, Belgium. wim.deborggraeve@kuleuven.be.
Biomaterials Science
|August 23, 2017
Summary
Nanocellulosic materials show promise as biocompatible inks for 3D bioprinting applications in tissue engineering. Further research into cellulose nanofibrils and nanocrystals is needed to explore their full potential in this emerging field.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Nanotechnology
Background:
- 3D bioprinting is a rapidly advancing technology with significant potential in tissue engineering and regenerative medicine.
- Cellulosic nanomaterials offer desirable properties like biocompatibility, biodegradability, and renewability, making them attractive for bioink development.
- Existing research on cellulose-based bioinks is growing, but the specific applications of cellulose nanofibrils and nanocrystals remain underexplored.
Purpose of the Study:
- To review and highlight the emerging applications of nanocellulosic materials in 3D bioprinting.
- To emphasize the potential of cellulose nanofibrils and nanocrystals as key components in advanced bioinks.
- To identify nanocellulose as a promising material for future developments in tissue engineering and regenerative medicine.
Main Methods:
- Literature review of recent studies on nanocellulosic materials and 3D bioprinting.
- Analysis of the properties of cellulose nanofibrils and nanocrystals relevant to bioink formulation.
- Synthesis of current knowledge on the use of cellulose-based materials in regenerative medicine applications.
Main Results:
- Nanocellulosic materials possess excellent biocompatibility, biodegradability, and renewability, crucial for 3D bioprinting bioinks.
- Cellulose nanofibrils and nanocrystals demonstrate potential for creating functional scaffolds for tissue regeneration.
- The unique properties of nanocellulose can be tailored for specific 3D bioprinting requirements.
Conclusions:
- Nanocellulosic materials represent a promising and emerging class of bioinks for 3D bioprinting.
- Further exploration of cellulose nanofibrils and nanocrystals is essential to unlock their full potential in regenerative medicine.
- This review underscores the significance of nanocellulose in advancing the field of 3D bioprinting for tissue engineering.

