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Updated: Feb 24, 2026

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Published on: September 20, 2024
Hyperkinetic motor seizures: a common semiology generated by two different cortical seizure origins
Lisa Vaugier1, Aileen McGonigal2, Stanislas Lagarde2
1APHM, Hôpital de la Timone, Service de neurophysiologie clinique, Marseille.
Abstract:
We report a 37-year-old, right-handed patient with drug-resistant focal epilepsy whose seizures were characterized by explosive hyperkinetic behaviour. Video-SEEG revealed bifocal organization of epilepsy with two distinct cortical origins of seizures: the right temporal pole and left temporal lateral and perisylvian cortex. Irrespective of the cortical pattern of seizure onset, the hyperkinetic semiology was extremely similar. This supports a major role for "final common pathway" subcortical circuits in the genesis of the hyperkinetic semiology in this patient.
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